How Long to Cook Meatloaf
Ground beef or turkey meatloaf, typically 2 to 3 pounds.
The Short Answer
In the oven at 350°F, meatloaf takes 50–70 minutes. The USDA-recommended safe internal temperature is 160°F, verified with an instant-read thermometer in the thickest part. Scroll down for all cooking methods, detailed instructions, and tips from the Professor.
Always verify with an instant-read thermometer inserted into the thickest part.
Cooking Methods
🔥 Oven
Temperature: 350°F
Time: 50–70 minutes
Rest: 10 minutes
For a 2-pound loaf. Shape into a freestanding loaf on a sheet pan for faster, more even cooking than in a loaf pan. Glaze in the last 15 minutes.
A freestanding meatloaf on a sheet pan cooks faster and more evenly than one squeezed into a loaf pan. The increased surface area also means more of that caramelized glaze.
Frequently Asked Questions
Common causes: not enough binder (eggs and breadcrumbs), overmixing (breaks down the meat), or not letting it rest before slicing. Mix gently and rest 10 minutes.
The Bottom Line
Meatloaf is straightforward to cook when you know the time and temperature. The most important number to remember is 160°F internal. An instant-read thermometer is the only reliable way to confirm doneness; color and firmness are not accurate indicators. Use the method that fits your equipment and schedule, and always let the food rest before cutting or serving. Resting allows juices to redistribute and carryover cooking to finish the job.
Source: USDA Safe Minimum Internal Temperatures | Last verified: March 19, 2026 | Our methodology