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How Long to Cook Pork Tenderloin

Whole pork tenderloin, typically 1 to 1.5 pounds.

The Short Answer

In the oven at 400°F, pork tenderloin takes 20–25 minutes. The USDA-recommended safe internal temperature is 145°F, verified with an instant-read thermometer in the thickest part. Scroll down for all cooking methods, detailed instructions, and tips from the Professor.

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Safe Internal Temperature 145°F

Always verify with an instant-read thermometer inserted into the thickest part.

Cooking Methods

🔥 Oven

Temperature: 400°F

Time: 20–25 minutes

Rest: 10 minutes

Sear all sides in a hot skillet first, then roast. Internal temp should reach 145 degrees F. Rest is critical for juiciness.

💨 Air Fryer

Temperature: 400°F

Time: 15–20 minutes

Rest: 10 minutes

Season well. May need to cut in half to fit. Flip halfway through.

🔥 Grill

Temperature: 450°F

Time: 15–20 minutes

Rest: 10 minutes

Sear over direct heat for 2 minutes per side, then move to indirect heat to finish.

The Professor
The Professor says:

Pork tenderloin dries out fast because it is so lean. Sear it first to lock in moisture, then roast gently. A 10-minute rest is not optional; the juices need to redistribute.

Frequently Asked Questions

145 degrees F with a 3-minute rest. The old recommendation of 160 is outdated and produces dry pork.

The Bottom Line

Pork Tenderloin is straightforward to cook when you know the time and temperature. The most important number to remember is 145°F internal. An instant-read thermometer is the only reliable way to confirm doneness; color and firmness are not accurate indicators. Use the method that fits your equipment and schedule, and always let the food rest before cutting or serving. Resting allows juices to redistribute and carryover cooking to finish the job.

Source: USDA Safe Minimum Internal Temperatures | Last verified: March 19, 2026 | Our methodology